| Item Type | Name |
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Concept
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MAP Kinase Signaling System
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Concept
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Ursodeoxycholic Acid
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Concept
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Glucose Transporter Type 4
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Concept
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Adverse Drug Reaction Reporting Systems
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Concept
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Portal System
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Concept
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Levulinic Acids
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Concept
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5-Aminolevulinate Synthetase
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Concept
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Aspartate Aminotransferases
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Concept
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Amino Acids
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Concept
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Amino Acid Substitution
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Concept
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Aminopyrine N-Demethylase
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Concept
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Amino Acid Sequence
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Concept
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Cytochrome P-450 Enzyme System
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Concept
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Fatty Acids, Monounsaturated
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Concept
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Ascorbic Acid
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Concept
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Pyruvic Acid
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Concept
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Nervous System Diseases
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Concept
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Ketoglutaric Acids
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Concept
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Biological Transport, Active
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Concept
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Regulatory Sequences, Nucleic Acid
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Concept
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Serotonin Plasma Membrane Transport Proteins
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Concept
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Peripheral Nervous System Diseases
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Concept
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Nucleic Acid Synthesis Inhibitors
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Concept
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Protein Transport
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Concept
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Glutamic Acid
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Concept
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Fatty Acid-Binding Proteins
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Concept
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Aminolevulinic Acid
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Concept
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Succinic Acid
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Concept
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Electron Transport
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Concept
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Hyaluronic Acid
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Concept
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Sequence Homology, Nucleic Acid
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Concept
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Heptanoic Acids
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Concept
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Nitrilotriacetic Acid
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Concept
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Young Adult
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Concept
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Cation Transport Proteins
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Concept
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Amino Acid Motifs
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Concept
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Hydroxyindoleacetic Acid
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Academic Article
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Porphyrogenic properties of the terpenes camphor, pinene, and thujone (with a note on historic implications for absinthe and the illness of Vincent van Gogh).
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Academic Article
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Intravenous heme-albumin in acute intermittent porphyria: evidence for repletion of hepatic hemoproteins and regulatory heme pools.
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Academic Article
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Iron and the liver.
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Academic Article
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Activation of the hepatocarcinogen aflatoxin B1 by forms of human hepatic cytochromes P-450: some do and some don't.
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Academic Article
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A randomized, controlled trial of treatment of alcoholic hepatitis with parenteral nutrition and oxandrolone. II. Short-term effects on nitrogen metabolism, metabolic balance, and nutrition.
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Academic Article
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Immunochemical studies of haem oxygenase. Preparation and characterization of antibodies to chick liver haem oxygenase and their use in detecting and quantifying amounts of haem oxygenase protein.
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Academic Article
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Synergistic induction of delta-aminolevulinate synthase by glutethimide and iron: relationship to the synergistic induction of heme oxygenase.
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Academic Article
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Cloning, sequencing and expression of cDNA for chick liver haem oxygenase. Comparison of avian and mammalian cDNAs and deduced proteins.
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Academic Article
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Purification and characterization of heme oxygenase from chick liver. Comparison of the avian and mammalian enzymes.
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Academic Article
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Antibodies against mitochondrial dehydrogenase complexes in primary biliary cirrhosis.
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Academic Article
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Mechanism of synergistic induction of hepatic heme oxygenase by glutethimide and iron: studies in cultured chick embryo liver cells.
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Academic Article
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Choline may be an essential nutrient in malnourished patients with cirrhosis.
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Academic Article
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Mechanism of iron potentiation of hepatic uroporphyria: studies in cultured chick embryo liver cells.
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Academic Article
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Immunochemical detection of different isoenzymes of cytochrome P-450 induced in chick hepatocyte cultures.
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Academic Article
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Hepatic microsomal function in rats with chronic dietary iron overload.
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Academic Article
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Uroporphyrin accumulation produced by halogenated biphenyls in chick-embryo hepatocytes. Reversal of the accumulation by piperonyl butoxide.
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Academic Article
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Hepatic heme and drug metabolism in rats with chronic mountain sickness.
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Academic Article
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Role of cytochrome P-450 in porphyria caused by halogenated aromatic compounds.
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Academic Article
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Regulation of hepatic haem metabolism. Disparate mechanisms of induction of haem oxygenase by drugs and metals.
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Academic Article
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Tryptophan 2,3-dioxygenase in chick embryo hepatocytes: studies in ovo and in culture.
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Academic Article
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Haem synthesis from exogenous 5-aminolaevulinate in cultured chick-embryo hepatocytes. Effects of inducers of cytochromes P-450.
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Academic Article
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Effects of therapeutic paracentesis on systemic and hepatic hemodynamics and on renal and hormonal function.
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Academic Article
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Induction of porphyria in cultured chick-embryo hepatocytes by halogenated aromatic compounds.
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Academic Article
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Hepatic heme synthesis in a new model of experimental hemochromatosis: studies in rats fed finely divided elemental iron.
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Academic Article
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Induction of 5-aminolaevulinate synthase by two- to five-carbon alcohols in cultured chick-embryo hepatocytes. Relationship to induction of cytochrome P-450.
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Academic Article
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Cytochrome P450 of small intestinal epithelial cells. Immunochemical characterization of the increase in cytochrome P450 caused by phenobarbital.
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Academic Article
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Conversion of 5-aminolaevulinate into haem by homogenates of human liver. Comparison with rat and chick-embryo liver homogenates.
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Academic Article
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Increased glutathione in cultured hepatocytes associated with induction of cytochrome P-450. Lack of effect of glutathione depletion on induction of cytochrome P-450 and delta-aminolevulinate synthase.
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Academic Article
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Inhibition of uroporphyrinogen decarboxylase by halogenated biphenyls in chick hepatocyte cultures. Essential role for induction of cytochrome P-448.
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Academic Article
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Formation of cytochrome P-450 containing haem or cobalt-protoporphyrin in liver homogenates of rats treated with phenobarbital and allylisopropylacetamide.
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Academic Article
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Effect of uroporphyrin on the spectral measurement of cytochrome P450.
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Academic Article
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Effect of hemochromatosis on hepatic cytochrome P450 and antipyrine metabolism in humans.
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Academic Article
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Distribution of iron in the liver predicts the response of chronic hepatitis C infection to interferon therapy.
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Academic Article
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Chronic leukocytoclastic vasculitis complicating HBV infection. Possible role of mutant forms of HBV in pathogenesis and persistence of disease.
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Academic Article
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Effects of mifepristone (RU-486) on heme metabolism and cytochromes P-450 in cultured chick embryo liver cells, possible implications for acute porphyria.
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Academic Article
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Repression of ALA synthase by heme and zinc-mesoporphyrin in a chick embryo liver cell culture model of acute porphyria.
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Academic Article
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Differential effects of metalloporphyrins on messenger RNA levels of delta-aminolevulinate synthase and heme oxygenase. Studies in cultured chick embryo liver cells.
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Academic Article
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Effects of hemopexin on heme-mediated repression of 5-aminolevulinate synthase and induction of heme oxygenase in cultured hepatocytes.
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Academic Article
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3,5,5-Trimethylhexanoylferrocene induction of heme oxygenase activity in normal hepatocytes.
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Academic Article
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Repression of hepatic delta-aminolevulinate synthase by heme and metalloporphyrins: relationship to inhibition of heme oxygenase.
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Academic Article
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Advances in understanding and treating 'the little imitator,' acute porphyria.
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Academic Article
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Hepatic 5-aminolevulinic acid synthase mRNA stability is modulated by inhibitors of heme biosynthesis and by metalloporphyrins.
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Academic Article
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Enhanced phenotypic expression of alpha-1-antitrypsin deficiency in an MZ heterozygote with chronic hepatitis C.
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Academic Article
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Inefficient recognition of autologous viral sequences by intrahepatic hepatitis C virus-specific cytotoxic T lymphocytes in chronically infected subjects.
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Academic Article
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Heme biosynthesis in a chicken hepatoma cell line (LMH): comparison with primary chick embryo liver cells (CELC).
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Academic Article
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Upstream regulatory elements in chick heme oxygenase-1 promoter: a study in primary cultures of chick embryo liver cells.
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Academic Article
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Extrahepatic manifestations of infection with hepatitis C virus.
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Academic Article
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Intestinal expression of genes involved in iron absorption in humans.
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Academic Article
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Management of nonalcoholic steatohepatitis: an analytic review.
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Academic Article
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Predicting cirrhosis in patients with hepatitis C based on standard laboratory tests: results of the HALT-C cohort.
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Academic Article
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Haem repression of the housekeeping 5-aminolaevulinic acid synthase gene in the hepatoma cell line LMH.
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Academic Article
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Serum alpha-fetoprotein levels in patients with advanced hepatitis C: results from the HALT-C Trial.
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Academic Article
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Autoimmune hepatitis triggered by statins.
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Academic Article
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Antiviral response of HCV genotype 1 to consensus interferon and ribavirin versus pegylated interferon and ribavirin.
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Academic Article
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Relationship of serum fibrosis markers with liver fibrosis stage and collagen content in patients with advanced chronic hepatitis C.
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Academic Article
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Vascular endothelium as a contributor of plasma sphingosine 1-phosphate.
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Academic Article
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Tissue-specific expression of ALA synthase-1 and heme oxygenase-1 and their expression in livers of rats chronically exposed to ethanol.
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Academic Article
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Case records of the Massachusetts General Hospital. Case 20-2008. A 57-year-old woman with abdominal pain and weakness after gastric bypass surgery.
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Academic Article
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Efficacy and safety of peginterferon alfa-2a/ribavirin in methadone maintenance patients: randomized comparison of direct observed therapy and self-administration.
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Academic Article
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Differential regulation of human ALAS1 mRNA and protein levels by heme and cobalt protoporphyrin.
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Academic Article
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Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States.
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Academic Article
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The neuromediator glutamate, through specific substrate interactions, enhances mitochondrial ATP production and reactive oxygen species generation in nonsynaptic brain mitochondria.
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Academic Article
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Coffee intake is associated with lower rates of liver disease progression in chronic hepatitis C.
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Academic Article
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CTL escape mutations of core protein are more frequent in strains of HBeAg negative patients with low levels of HBV DNA.
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Academic Article
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Predicting clinical and histologic outcomes based on standard laboratory tests in advanced chronic hepatitis C.
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Academic Article
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Iron increases HMOX1 and decreases hepatitis C viral expression in HCV-expressing cells.
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Academic Article
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Drug-induced liver injury associated with statins.
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Academic Article
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A functional serotonin transporter gene polymorphism and depressive effects associated with interferon-alpha treatment.
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Academic Article
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Discovery of putative pancreatic cancer biomarkers using subcellular proteomics.
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Academic Article
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A phase 1/2, dose-escalation trial of deferasirox for the treatment of iron overload in HFE-related hereditary hemochromatosis.
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Academic Article
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Effect of bovine serum albumin on mitochondrial respiration in the brain and liver of mice and rats.
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Academic Article
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Iron levels in hepatocytes and portal tract cells predict progression and outcomes of patients with advanced chronic hepatitis C.
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Academic Article
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Structural analysis of heme proteins: implications for design and prediction.
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Academic Article
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Lon peptidase 1 (LONP1)-dependent breakdown of mitochondrial 5-aminolevulinic acid synthase protein by heme in human liver cells.
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Academic Article
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Extended interferon-alpha therapy accelerates telomere length loss in human peripheral blood T lymphocytes.
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Academic Article
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Effects of a single dose of oral iron on hepcidin concentrations in human urine and serum analyzed by a robust LC-MS/MS method.
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Academic Article
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Subcellular tissue proteomics of hepatocellular carcinoma for molecular signature discovery.
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Academic Article
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YKL-40 genetic polymorphisms and the risk of liver disease progression in patients with advanced fibrosis due to chronic hepatitis C.
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Academic Article
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A naturally occurring human/hepatitis E recombinant virus predominates in serum but not in faeces of a chronic hepatitis E patient and has a growth advantage in cell culture.
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Academic Article
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Neonatal androgenization exacerbates alcohol-induced liver injury in adult rats, an effect abrogated by estrogen.
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Academic Article
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Cytoskeletal proteins: shaping progression of hepatitis C virus-induced liver disease.
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Academic Article
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Loss-of-function ferrochelatase and gain-of-function erythroid-specific 5-aminolevulinate synthase mutations causing erythropoietic protoporphyria and x-linked protoporphyria in North American patients reveal novel mutations and a high prevalence of X-linked protoporphyria.
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Academic Article
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Presentation and outcomes with clinically apparent interferon beta hepatotoxicity.
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Academic Article
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Chronic hepatitis E with neurologic manifestations and rapid progression of liver fibrosis in a liver transplant recipient.
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Academic Article
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Catechins in dietary supplements and hepatotoxicity.
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Academic Article
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Circadian rhythms in acute intermittent porphyria--a pilot study.
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Academic Article
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Hepatic histological findings in suspected drug-induced liver injury: systematic evaluation and clinical associations.
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Academic Article
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Drug-induced liver injury with autoimmune features.
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Academic Article
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Acute porphyrias in the USA: features of 108 subjects from porphyrias consortium.
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Academic Article
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Risk factors for severe or fatal drug-induced liver injury from amoxicillin-clavulanic acid.
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Academic Article
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Differences in glycogen, lipids, and enzymes in livers from rats flown on COSMOS 2044.
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Academic Article
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Recent insights into the biological functions of liver fatty acid binding protein 1.
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Academic Article
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Genetic factors that affect nonalcoholic fatty liver disease: A systematic clinical review.
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Academic Article
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BMP4 promotes metastasis of hepatocellular carcinoma by an induction of epithelial-mesenchymal transition via upregulating ID2.
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Grant
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Research Network for Drug-Induced Liver Disease
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Grant
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HEPATITIS C CLINICAL TRIAL-CLINICAL CENTERS
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Grant
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Regulation of Hepatic Heme Metabolism
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Grant
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HEPATIC HEME, CYTOCHROME P-450 AND DRUG METABOLISM
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Academic Article
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Clinical, Biochemical, and Genetic Characterization of North American Patients With Erythropoietic Protoporphyria and X-linked Protoporphyria.
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Academic Article
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BMP4 promotes oxaliplatin resistance by an induction of epithelial-mesenchymal transition via MEK1/ERK/ELK1 signaling in hepatocellular carcinoma.
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Academic Article
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miR-122 inhibition in a human liver organoid model leads to liver inflammation, necrosis, steatofibrosis and dysregulated insulin signaling.
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Academic Article
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Peripheral Neuropathy and the Ceruloplasmin Gene.
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Academic Article
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Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Cav3.2?T-type voltage-gated calcium channels and Ca2+ influx.
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Academic Article
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International Porphyria Molecular Diagnostic Collaborative: an evidence-based database of verified pathogenic and benign variants for the porphyrias.
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Academic Article
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Severe and protracted cholestasis in 44 young men taking bodybuilding supplements: assessment of genetic, clinical and chemical risk factors.
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Academic Article
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Pilot study of mitochondrial bioenergetics in subjects with acute porphyrias.
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Academic Article
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Sex differences in vascular reactivity in mesenteric arteries from a mouse model of acute intermittent porphyria.
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Academic Article
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Phase 1 Trial of an RNA Interference Therapy for Acute Intermittent Porphyria.
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Academic Article
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Strong correlation of ferrochelatase enzymatic activity with Mitoferrin-1 mRNA in lymphoblasts of patients with protoporphyria.
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Academic Article
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Benefits of prophylactic heme therapy in severe acute intermittent porphyria.
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